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The Centre for Spinal Studies and Surgery (CSSS) places a great importance on both clinical and basic research, striving for constant improvement and development.

Several of our consultants actively take part in research with a dedicated team of research fellows that are active in the consultant's field of interest and a specialised team supporting the administrative needs of the department's clinical trials. 

Below is a list of ongoing clinical trials in the CSSS:


GSTSG Global Spinal Tumour Registry 

This study is a prospective analysis of all consenting patients who undergo spinal surgery for metastatic spine disease in surgical units in the UK, Japan, Germany, France, Italy and Denmark. Patient data will be stored on a secure UK database, and analysed by the chief investigator, to determine factors which are associated with good and bad patient outcomes, determine the usefulness of different surgical techniques, and suggest prognostic indicators which will influence future patient management.  




SCI-POEM - European Multicenter Study

SCI-POEM, sponsored by AOSpine, is a far-reaching study comprising of 17 clinics in 12 countries all across Europe.

The objective of the study is to evaluate if decompressive spinal surgery occurring within 12 hours (post-injury) of a traumatic spinal cord injury can provide superior neurological motor outcomes when compared to late decompression occurring more that 12 hours (and within 14 days) of the injury.





The purpose of this study, sponsored by the AO Foundation group, is an evaluation of the Modern Luqué Trolley growth guiding system vs. conventional treatment of early onset scoliosis patients.





The Scoli-Risk-1 database is a prospective, international, observational, multicentre study, run by the AO Clinical Investigation and Documentation group on behalf of AOSpine and the Scoliosis Research Society.





The OGmend system developed by Woven Orthopedic Technologies is the first piece of technology in the world specifically designed to address loss of screw fixation by focusing on the screw-to-bone interface. By utilising a unique biopolymer, this devices increases the surface area contact between the bone and screw, distribute load transfer, help bone healing and remodeling, promote bone ingrowth, and enhance fixation in both the short-term and the long-term.






NERVES is a randomised controlled trial, funded by the National Institute for Health Research's (NIHR) Health Technology Assessment Programme and sponsored by The Walton Centre NHS Foundation Trust, to compare the clinical and cost effectiveness of transforaminal epidural steroid injection to surgical microdiscectomy for treatment of sciatica caused by a prolapsed intervertebral disc.




If you wish for the Centre for Spinal Studies and Surgery to become involved on a future or ongoing trial, please do not hesitate to contact the centre's Research Team at:


Last updated: January 2018